To improve microbial fermentation as an efficient way to sustainably produce green
chemicals from renewable resources, novel production organisms are being explored.
Extremophiles, in general, and moderate thermophiles in particular, offer important
advantages over well-known mesophilic biotechnology hosts, such as Escherichia coli and
Saccharomyces cerevisiae. These advantages include robust performance at temperatures
that allow high substrate and product solubility, decreased contamination risk and growth …