Switching of cell growth/detachment on heparin-functionalized thermoresponsive surface for rapid cell sheet fabrication and manipulation

Y Arisaka, J Kobayashi, M Yamato, Y Akiyama… - Biomaterials, 2013 - Elsevier
Heparin-functionalized poly (N-isopropylacrylamide-co-2-carboxyisopropylacrylamide)[P
(IPAAm-co-CIPAAm)] grafted surface was designed for the switching of cell
growth/detachment, achieved by the regulation of affinity binding between basic fibroblast
growth factor (bFGF) and immobilized heparin through the temperature-dependent
conformational change of grafted P (IPAAm-co-CIPAAm) chains. At 37° C, bFGF-bound
heparin-thermoresponsive surfaces were able to hold the two-to three-fold number of mouse …

[引用][C] Switching of cell growth/detachment on heparin-functionalized thermoresponsive surface for rapid cell sheet fabrication and manipulation

有坂慶紀 - 2013 - ci.nii.ac.jp
CiNii 博士論文 - Switching of cell growth/detachment on heparin-functionalized
thermoresponsive surface for rapid cell sheet fabrication and manipulation … Switching of
cell growth/detachment on heparin-functionalized thermoresponsive surface for rapid cell
sheet fabrication and manipulation 迅速な細胞シート作製を目指したヘパリン機能化温度応答性
表面上での細胞増殖/細胞剥離の制御 … Switching of cell growth/detachment on heparin-functionalized
thermoresponsive surface for rapid cell sheet fabrication and manipulation …
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