Synchronized neural oscillations and the pathophysiology of Parkinson's disease
Oscillatory activities across multiple frequency bands and their cross-frequency interactions
within spatially segregated loops of the basal ganglia-thalamo-cortical system may relate to
distinct components of clinical impairment, both motor and non-motor. It is hoped that this
characterization will lead to improved interventions like deep brain stimulation, tailored to
specific components of clinical impairment and their associated spatial and spectral
signatures.
within spatially segregated loops of the basal ganglia-thalamo-cortical system may relate to
distinct components of clinical impairment, both motor and non-motor. It is hoped that this
characterization will lead to improved interventions like deep brain stimulation, tailored to
specific components of clinical impairment and their associated spatial and spectral
signatures.
Summary
Oscillatory activities across multiple frequency bands and their cross-frequency interactions within spatially segregated loops of the basal ganglia-thalamo-cortical system may relate to distinct components of clinical impairment, both motor and non-motor. It is hoped that this characterization will lead to improved interventions like deep brain stimulation, tailored to specific components of clinical impairment and their associated spatial and spectral signatures.
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