Synthesis, characterization and in-vitro anti-inflammatory activity of some substituted 1, 2, 3, 4 tetrahydropyrimidine derivatives
AS Gondkar, VK Deshmukh, SR Chaudhari - Drug Invention Today, 2013 - Elsevier
Background & aim Pyrimidines represent a broad class of compounds, which have received
considerable attention due to their wide range of biological activities such as, anti-
inflammatory, COX inhibitor, anticancer, antiallergic and analgesic. On the basis of
exhaustive literature review and PASS predictions, it has been found that substituted 1, 2, 3,
4 tetrahydropyrimidine derivatives have good potential to exhibit in vitro anti-inflammatory
activity. Method The toxicity and pharmacological activities of synthesized compounds were …
considerable attention due to their wide range of biological activities such as, anti-
inflammatory, COX inhibitor, anticancer, antiallergic and analgesic. On the basis of
exhaustive literature review and PASS predictions, it has been found that substituted 1, 2, 3,
4 tetrahydropyrimidine derivatives have good potential to exhibit in vitro anti-inflammatory
activity. Method The toxicity and pharmacological activities of synthesized compounds were …
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