Synthesis and antibacterial activity of N4-mono alkyl derivatives of novel glycopeptide LYV07ww01
C Shao, W Zhou, S Zhang, W Wei, L Ruan, Y Jin… - Bioorganic & medicinal …, 2011 - Elsevier
Bioorganic & medicinal chemistry letters, 2011•Elsevier
Thirty-one N4-mono alkyl derivatives of novel glycopeptide LYV07ww01 were synthesized
by the reductive alkylation and their in vitro antibacterial activity was tested. The benzyl
derivatives showed potent activity, especially against vancomycin-resistant enterococci and
penicillin-resistant Streptococcus pneumoniae.
by the reductive alkylation and their in vitro antibacterial activity was tested. The benzyl
derivatives showed potent activity, especially against vancomycin-resistant enterococci and
penicillin-resistant Streptococcus pneumoniae.
Thirty-one N4-mono alkyl derivatives of novel glycopeptide LYV07ww01 were synthesized by the reductive alkylation and their in vitro antibacterial activity was tested. The benzyl derivatives showed potent activity, especially against vancomycin-resistant enterococci and penicillin-resistant Streptococcus pneumoniae.
Elsevier
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