Synthesis and antimicrobial evaluation of ferulic acid derivatives
A series of ferulic acid derivatives (1–38) was synthesized and characterized by
physicochemical and spectral means. The synthesized compounds were evaluated in vitro
for their antimicrobial activity against different Gram-positive and Gram-negative bacterial
and fungal strains by the tube dilution method. Results of antimicrobial screening indicated
that compound 1 was the most active antimicrobial agent (pMIC am= 1.83 μM/ml).
physicochemical and spectral means. The synthesized compounds were evaluated in vitro
for their antimicrobial activity against different Gram-positive and Gram-negative bacterial
and fungal strains by the tube dilution method. Results of antimicrobial screening indicated
that compound 1 was the most active antimicrobial agent (pMIC am= 1.83 μM/ml).
Abstract
A series of ferulic acid derivatives (1–38) was synthesized and characterized by physicochemical and spectral means. The synthesized compounds were evaluated in vitro for their antimicrobial activity against different Gram-positive and Gram-negative bacterial and fungal strains by the tube dilution method. Results of antimicrobial screening indicated that compound 1 was the most active antimicrobial agent (pMICam = 1.83 μM/ml).
Springer
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