Synthesis and application of the MCM-41 and SBA-15 as matrices for in vitro efavirenz release study

RA Jesus, AS Rabelo, RT Figueiredo… - Journal of Drug Delivery …, 2016 - Elsevier
The mesoporous materials in particular the Mobil Composition of Matter No. 41 (MCM-41)
and Santa Barbara Amorphous-15 (SBA-15) are considered promising as devices for
controlled drug release, because of properties such as hexagonal arrangement, high
surface area and non-cytotoxic properties. The materials were synthesized under
hydrothermal method and efavirenz (EFZ) was used for testing of controlled release. The
material obtained was ordered and had high surface area even after of the incorporation of …
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