synthesized and their trichomonacidal, antichagasic and antineoplastic properties studied.
Five derivatives (5, 6, 8, 9 and 17) showed remarkable trichomonacidal activity against
Trichomonas vaginalis at 10μg/mL concentration. Three compounds (8, 10, 11) exhibited
interesting antichagasic activity and these same compounds moderate antineoplastic activity
against TK-10 and HT-29 cell lines. Unspecific cytotoxicity against macrophages has also …