Synthesis and in vivo antihyperglycemic activity of nature-mimicking furanyl-2-pyranones in STZ-S model
Bioorganic & medicinal chemistry letters, 2007•Elsevier
Various nature-mimicking pyranones such as 6-(2, 5-dimethylfuran-3-yl)-pyran-2-one and 6-
(furan-2-yl)-pyran-2-one derivatives were synthesized and evaluated for their in vivo
antihyperglycemic activity in sucrose-loaded streptozotocin-induced diabetic rat model. Five
of the test compounds showed significant lowering of plasma glucose level in STZ-S model.
(furan-2-yl)-pyran-2-one derivatives were synthesized and evaluated for their in vivo
antihyperglycemic activity in sucrose-loaded streptozotocin-induced diabetic rat model. Five
of the test compounds showed significant lowering of plasma glucose level in STZ-S model.
Various nature-mimicking pyranones such as 6-(2,5-dimethylfuran-3-yl)-pyran-2-one and 6-(furan-2-yl)-pyran-2-one derivatives were synthesized and evaluated for their in vivo antihyperglycemic activity in sucrose-loaded streptozotocin-induced diabetic rat model. Five of the test compounds showed significant lowering of plasma glucose level in STZ-S model.
Elsevier
以上显示的是最相近的搜索结果。 查看全部搜索结果