Synthesis and spectroscopic characterisation of 2-(2′-hydroxyphenyl) benzazole isothiocyanates as new fluorescent probes for proteins
Three new benzazole isothiocyanate (BzITC) fluorescent dyes, 2-(5′-isothiocyanate-2′-
hydroxyphenyl) benzoxazole, 2-(5′-isothiocyanate-2′-hydroxyphenyl) benzimidazole and
2-(5′-isothiocyanate-2′-hydroxyphenyl) oxazole [4, 5-b] pyridine, were synthesised,
purified until optical purity grade and characterised by elemental analysis, 1 H NMR, IR, UV–
VIS and fluorescence spectroscopy. These dyes exhibit an intense fluorescence emission
with a large Stokes shift due to an excited state intramolecular proton transfer (ESIPT) …
hydroxyphenyl) benzoxazole, 2-(5′-isothiocyanate-2′-hydroxyphenyl) benzimidazole and
2-(5′-isothiocyanate-2′-hydroxyphenyl) oxazole [4, 5-b] pyridine, were synthesised,
purified until optical purity grade and characterised by elemental analysis, 1 H NMR, IR, UV–
VIS and fluorescence spectroscopy. These dyes exhibit an intense fluorescence emission
with a large Stokes shift due to an excited state intramolecular proton transfer (ESIPT) …
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