Synthesis of Polysubstituted 3‐Iodopyrans by Electrophilic Cyclization
YX Xie, ZY Yan, DZ Wang, LY Wu, B Qian, XY Liu… - 2009 - Wiley Online Library
YX Xie, ZY Yan, DZ Wang, LY Wu, B Qian, XY Liu, YM Liang
2009•Wiley Online LibraryA variety of polysubstituted 3‐iodopyrans were readily prepared in good to excellent yield
under mild reaction conditions by the reaction of alkynyl carboxamides with ICl, I2, and NIS.
The products obtained from this process are versatile materials that can be used to construct
other complex functionalized pyran structures of importance. The occurrence of the pyranyl
group in both natural products and pharmaceuticals confers important value to this study.(©
Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
under mild reaction conditions by the reaction of alkynyl carboxamides with ICl, I2, and NIS.
The products obtained from this process are versatile materials that can be used to construct
other complex functionalized pyran structures of importance. The occurrence of the pyranyl
group in both natural products and pharmaceuticals confers important value to this study.(©
Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Abstract
A variety of polysubstituted 3‐iodopyrans were readily prepared in good to excellent yield under mild reaction conditions by the reaction of alkynyl carboxamides with ICl, I2, and NIS. The products obtained from this process are versatile materials that can be used to construct other complex functionalized pyran structures of importance. The occurrence of the pyranyl group in both natural products and pharmaceuticals confers important value to this study. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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