Synthesis of current pediatric urinary microbiome research

LM Jeries, TA Sysoeva, L Karstens, MS Kelly - Frontiers in Pediatrics, 2024 - frontiersin.org
Frontiers in Pediatrics, 2024frontiersin.org
The human urinary bladder hosts a complex microbial community of low biomass referred to
as the urobiome. While the composition of the urobiome has been investigated in adults for
over a decade now, only a few studies have considered the presence and composition of
the urobiome in children. It is critical to explore how the urobiome develops throughout the
life span and how it changes in the presence of various health conditions. Therefore, we set
to review the available data on pediatric urobiome composition and its development with …
The human urinary bladder hosts a complex microbial community of low biomass referred to as the urobiome. While the composition of the urobiome has been investigated in adults for over a decade now, only a few studies have considered the presence and composition of the urobiome in children. It is critical to explore how the urobiome develops throughout the life span and how it changes in the presence of various health conditions. Therefore, we set to review the available data on pediatric urobiome composition and its development with age and disease. In addition, we focused on identifying and reporting specific gaps in our knowledge of the pediatric urobiome that we hope will be addressed by future studies in this swiftly developing field with fast-improving methods and consensus.
Frontiers
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