… are discussed in this Review, and the progress in medical Raman imaging since 2012 is …
background in Raman spectra of biological samples, near-infrared lasers are usually used for …

… in the field for obtaining Raman spectra using a microspectrometer. As examples of the
range of biological samples that can be analyzed, we provide instructions for acquiring Raman …

… Both features enable mapping of the distributions of molecules … to small-molecule imaging
by using tiny Raman-active tags such … During Raman imaging of a biological sample, the cell …

… the new methodologies, namely infrared and Raman spectroscopy. … Raman spectroscopy
can complement histopathology and reveal information that is available in classical methods …

… The measured spectra contain peaks that are known to occur in biological samples, such
as the ring breathing of phenylalanine ( 1000 cm − 1 ), C H 2 deformation ( 1451 cm − 1 ) and …

… molecules. Vibrational spectroscopy based on spontaneous Raman scattering is widely used
for label-free analysis … However, the Raman process is a weak effect, limiting its application …

… the application of the Raman spectroscopic technique for analysis of biological tissue. The
… 1), a process known as UV resonance Raman spectroscopy (UVRR). In biological materials, …

… of Raman imaging of small molecules using Raman tags for chemical biology research. …
drastically increased the utility of Raman spectra for analyzing complex biological samples. …

… small-molecule drugs in live biological systems ranging from … biology, thus allowing real-time
imaging of small-molecule … chemical imaging, a valuable technique in the era of “omics”. …

… So far, this near-field technique has been used to investigate very different materials ranging
from carbon-based and 2D materials to catalytic reactions and biological specimen. In all …