… We have identified NELL1 as a novel disease gene for Crohn disease (CD), a result that
was obtained in a genome-wide case-control association scan with 116,161 SNPs and by …

… We have identified NELL1 as a novel disease gene for Crohn disease (CD), a result that
was obtained in a genome-wide casecontrol association scan with 116,161 SNPs and by …

… can shed light on novel genotype–phenotype associations. Results from … of genes and
diseases at a systemic level. Clearly, … NELL1 was among the 10 associated genes identified by …

… GWAS novel associations with two genes … NELL1 gene do not concur with those reported
in the original GWAS. Both the lead SNP rs1793004 and the SNP identified via fine-mapping (…

… colon, this study identified novel target genes for IBD- and CRC-associated genetic variants.
… eQTL analysis to correct for unmeasured yet systematic variation in gene expression levels. …

… Novel Crohn’s disease locus identified by genome-wide … Systematic association
mapping identifies NELL1 as a novel IBD disease gene. PLoS ONE . 2007; 2: e691. …

… a better understanding of the etiology of inflammatory bowel disease (IBD). While over 240
… Association analyses identified novel variants in the NOD2 and SNX20 genes to be linked …

… at identifying novel therapeutic targets among P/PIs. During the first stage of IBDase described
here, we systematically reviewed all published genetic linkage and association studies in …

… (CD) is a chronic relapsing inflammatory bowel disease of … in the NOD2 gene, which
determines the immune response to … However, the mechanisms by which the NELL1 gene product …

… and systemic bone regeneration, the synergistic effect of Nell-1 … emerging and novel functional
properties of Nell-1 in oral-… With the Nell-1 gene being originally identified from a human …