Systemic treatments for eczema: a network meta‐analysis

R Sawangjit, P Dilokthornsakul… - Cochrane Database …, 2020 - cochranelibrary.com
Cochrane Database of Systematic Reviews, 2020cochranelibrary.com
Background Eczema is a common and chronic, relapsing, inflammatory skin disorder. It
seriously impacts quality of life and economic outcomes, especially for those with moderate
to severe eczema. Various treatments allow sustained control of the disease; however, their
relative benefit remains unclear due to the limited number of trials directly comparing
treatments. Objectives To assess the comparative efficacy and safety of different types of
systemic immunosuppressive treatments for moderate to severe eczema using NMA and to …
Background
Eczema is a common and chronic, relapsing, inflammatory skin disorder. It seriously impacts quality of life and economic outcomes, especially for those with moderate to severe eczema. Various treatments allow sustained control of the disease; however, their relative benefit remains unclear due to the limited number of trials directly comparing treatments.
Objectives
To assess the comparative efficacy and safety of different types of systemic immunosuppressive treatments for moderate to severe eczema using NMA and to generate rankings of available systemic immunosuppressive treatments for eczema according to their efficacy and safety.
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