[HTML][HTML] Systems biology and systems genetics—novel innovative approaches to study host–pathogen interactions during influenza infection
H Kollmus, E Wilk, K Schughart - Current opinion in virology, 2014 - Elsevier
Highlights•Large scale omics have created the basis for influenza systems biology.•Systems
genetics makes an important contribution to systems biology.•Experimental animal models
lead the way to systems medicine.•In silico models discover new molecular pathways
correlated with disease.•Systems biology leads to new prevention and treatment strategies
for humans.Influenza represents a serious threat to public health with thousands of deaths
each year. A deeper understanding of the host–pathogen interactions is urgently needed to …
genetics makes an important contribution to systems biology.•Experimental animal models
lead the way to systems medicine.•In silico models discover new molecular pathways
correlated with disease.•Systems biology leads to new prevention and treatment strategies
for humans.Influenza represents a serious threat to public health with thousands of deaths
each year. A deeper understanding of the host–pathogen interactions is urgently needed to …
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