… Yet, how mRNA vaccines stimulate the immune system to … Here we used a systems vaccinology
approach to … volunteers who were vaccinated with the Pfizer–BioNTech mRNA vaccine (…

… with other vaccines,” … BNT162b2 were broadly similar”, instead of the original “Although the
day-1 response to the first dose of BNT162b2 showed little overlap with that of other vaccines…

… changes induced by BNT162b2 vaccination. We performed bulk mRNA sequencing of 185
samples … pathways induced by BNT162b2 that were unique or shared with other vaccines, we …

… studies in humans that assessed the efficacy of SARS-CoV-2 mRNA … The individual’s
immune system will then mount a robust … licensed mRNA vaccines mRNA-1273 and BNT162b2, …

… Human immune responses to COVID-19 vaccines display a … biology analysis of the immune
responses to BNT162b2 in a … the immunogenicity of mRNA COVID-19 vaccines and might …

… and BNT162b2 that correlate with antigen-specific antibody and T cell responses … vaccine
reactogenicity. Unexpectedly, we observe that vaccination with ChAdOx1-S, but not BNT162b2…

… of two highly efficacious mRNA vaccines in less than a year since the emergence of
SARS-CoV-2 represents a landmark in vaccinology. However, reports of waning vaccine efficacy …

… human population. In this study, a reverse vaccinology approach was implemented to design
a mRNA … optimized protein expression in the host expression system were calculated: (1) …

… symptoms. The high incidence of AEs is likely caused by the pro-inflammatory nature of mRNA
vaccines; … The same criteria used for the clinical trial of the BNT162b2 mRNA vaccine was …

… induced by BNT162b2 after both primary and booster vaccines in … In this study, we found
that BNT162b2 mRNA could be … immune system senses the BNT162b2 mRNA vaccine and …