TLR4 and NKT cell synergy in immunotherapy against visceral leishmaniasis
S Karmakar, SK Bhaumik, J Paul, T De - PLoS pathogens, 2012 - journals.plos.org
NKT cells play an important role in autoimmune diseases, tumor surveillance, and infectious
diseases, providing in most cases protection against infection. NKT cells are reactive to
CD1d presented glycolipid antigens. They can modulate immune responses by promoting
the secretion of type 1, type 2, or immune regulatory cytokines. Pathogen-derived signals to
dendritic cells mediated via Toll like Receptors (TLR) can be modulated by activated
invariant Natural Killer T (iNKT) cells. The terminal β-(1–4)-galactose residues of glycans …
diseases, providing in most cases protection against infection. NKT cells are reactive to
CD1d presented glycolipid antigens. They can modulate immune responses by promoting
the secretion of type 1, type 2, or immune regulatory cytokines. Pathogen-derived signals to
dendritic cells mediated via Toll like Receptors (TLR) can be modulated by activated
invariant Natural Killer T (iNKT) cells. The terminal β-(1–4)-galactose residues of glycans …
TLR4 and NKT cell synergy in immunotherapy against visceral leishmaniasis.
SK Subir Karmakar, SK Bhaumik, JP Joydeep Paul… - 2012 - cabidigitallibrary.org
NKT cells play an important role in autoimmune diseases, tumor surveillance, and infectious
diseases, providing in most cases protection against infection. NKT cells are reactive to
CD1d presented glycolipid antigens. They can modulate immune responses by promoting
the secretion of type 1, type 2, or immune regulatory cytokines. Pathogen-derived signals to
dendritic cells mediated via Toll like Receptors (TLR) can be modulated by activated
invariant Natural Killer T (iNKT) cells. The terminal β-(1-4)-galactose residues of glycans can …
diseases, providing in most cases protection against infection. NKT cells are reactive to
CD1d presented glycolipid antigens. They can modulate immune responses by promoting
the secretion of type 1, type 2, or immune regulatory cytokines. Pathogen-derived signals to
dendritic cells mediated via Toll like Receptors (TLR) can be modulated by activated
invariant Natural Killer T (iNKT) cells. The terminal β-(1-4)-galactose residues of glycans can …
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