TRP4 (CCE1) protein is part of native calcium release-activated Ca2+-like channels in adrenal cells
…, G Schroth, O Kretz, W Nastainczyk, A Cavalié… - Journal of Biological …, 2000 - ASBMB
Mammalian TRP proteins have been implicated to function as ion channel subunits
responsible for agonist-induced Ca 2+ entry. To date, TRP proteins have been extensively
studied by heterologous expression giving rise to diverse channel properties and activation
mechanisms including store-operated mechanisms. However, the molecular structure and
the functional properties of native TRP channels still remain elusive. Here we analyze the
properties of TRP4 (CCE1) channels in their native environment and characterize TRP …
responsible for agonist-induced Ca 2+ entry. To date, TRP proteins have been extensively
studied by heterologous expression giving rise to diverse channel properties and activation
mechanisms including store-operated mechanisms. However, the molecular structure and
the functional properties of native TRP channels still remain elusive. Here we analyze the
properties of TRP4 (CCE1) channels in their native environment and characterize TRP …