Müller glia, a pillar of metabolic, volume regulatory and immune/inflammatory signaling in
the mammalian retina, are among the earliest responders to mechanical stressors in the
eye. Ocular trauma, edema, detachment and glaucoma evoke early inflammatory activation
of Müller cells yet the identity of their mechanotransducers and signaling mechanisms
downstream remains unknown. Here, we investigate expression of genes that encode
putative stretch-activated calcium channels (SACs) in mouse Müller cells and study their …