The safety and efficacy of 0.1% tacrolimus ointment for the treatment of psoriasis on the face,
intertriginous areas, or both were evaluated in an open-label, clinical trial of 21 patients with
psoriasis. Patients applied 0.1% tacrolimus ointment twice daily for 8 weeks. Efficacy was
assessed through the investigator's evaluation of the individual signs and symptoms of
psoriasis, and the physician's global evaluation of change in disease status. Assessments of
cutaneous atrophy and other adverse events were made throughout the study to evaluate …