… induction of c-Myc and the subsequent activation of the anti-apoptotic protein Mcl-1. Activation
of Myc might occur in other types of leukocyte that are infected by Theileria and in other …

… c-Myc is a key feature of Theileria-induced transformation, and inhibition of c-Myc in Theileria-…
Taken together, the results of these studies point to an important role for JNK signaling in …

… process that takes place before … myc-tagged versions of Polo-box domain (myc-PBD, wild
type), H538A/K540A mutant PBD (myc-PBD H538A/K540A), or catalytically inactive Plk1 (myc-…

… -Myc acts at least in part through regulation of the gene encoding the anti-apoptotic protein,
MCl-1. Upregulation of c-Myc may … the view was taken that, since Theileria-induced leukocyte …

The intracellular parasite Theileria parva infects and transforms bovine T‐cells, inducing
their uncontrolled proliferation and spread in non‐lymphoid as well as lymphoid tissues. This …

… , but loss of PKB activity is not lethal, as Bad is … However, an important take home message
is that hepatocyte … Thus, one of the ways Theileria induces high levels of c-Myc involves a GM-…

… c-myc-driven 75 transcription of anti-apoptotic genes16–18. Theileria transformation …
For example, Theileria-induced tumor dissemination is regulated by 78 changes in TGF-β2 …

The invasion of Theileria sporozoites into bovine leukocytes is … Theileria infection induces
host cell transformation, … , are constitutively activated in Theileria-infected cells and contribute …

… Theileria species of Apicomplexa are particularly masterly manipulators of host cell states.
Two Theileria … Infection by Theileria causes a lymphoproliferative disease in cows with clinical …

… Taken together, these in vivo data show that ablation of Theileria-dependent c-Jun … Myc
induction (19). Thus, important B cell survival factors are induced following JNK activation in both …