[图书][B] Tandem repeat polymorphisms: genetic plasticity, neural diversity and disease

AJ Hannan - 2013 - books.google.com
… of tandem repeat polymorphisms (TRPs) in genetic plasticity, … , neural diversity, brain
function, dysfunction and disease. … tandem repeats in the human genome and their polymorphic

Tandem repeat polymorphisms: mediators of genetic plasticity, modulators of biological diversity and dynamic sources of disease susceptibility

AJ Hannan - Tandem Repeat Polymorphisms: Genetic Plasticity …, 2012 - Springer
… a rich source of genetic diversity that can facilitate evolutionary … tandem repeats may provide
an important template for stochastic genetic variation, which could in turn generate diversity

Tandem repeats mediating genetic plasticity in health and disease

AJ Hannan - Nature Reviews Genetics, 2018 - nature.com
neurological disorders), and emerging data suggest that tandem repeat polymorphisms (…
I discuss the putative functions of STRs across diverse species and their causative roles in a …

Tandem repeat polymorphisms

AJ Hannan - Tandem Repeat Polymorphisms: Genetic Plasticity …, 2013 - Springer
… As we begin a new genetic … of tandem repeats and their polymorphic variants will no doubt
continue to enhance our understanding of genetic plasticity, neural diversity and disease. …

Revisiting tandem repeats in psychiatric disorders from perspectives of genetics, physiology, and brain evolution

X Xiao, CY Zhang, Z Zhang, Z Hu, M Li, T Li - Molecular Psychiatry, 2022 - nature.com
… primarily by neurological presentations [25,26,27]. These … contribute to disease susceptibility
via diverse mechanisms (eg… tandem repeats versus 70% at highly polymorphic repeats, this …

[HTML][HTML] TRPing up the genome: Tandem repeat polymorphisms as dynamic sources of genetic variability in health and disease

AJ Hannan - Discovery medicine, 2010 - discoverymedicine.com
… monogenic disorders, which mainly affect the nervous system… tandem repeats in the human
genome and their polymorphic … influence functional diversity and disease susceptibility. …

A new look at the challenging world of tandem repeats

V De Fonzo, E Bersani, F Aluffi-Pentini, V Parisi - Medical hypotheses, 2000 - Elsevier
… has shown a correlation between some genetic diseases, often of the … Frothingham R.,
Meeker-O’Connell WA Genetic diversity in the … A 40-nucleotide repeat polymorphism in the human …

Evolution of simple sequence repeats as mutable sites

DG King - Tandem repeat polymorphisms: genetic plasticity …, 2012 - Springer
… SSRs in neurological as well as other functions. But apart from the evident role of repeat
expansion in several human neurological disorders, … near a gene with any neurological function. …

Selective neurodegeneration, neuropathology and symptom profiles in Huntington's disease

HJ Waldvogel, D Thu, V Hogg, L Tippett… - … Genetic Plasticity, Neural …, 2012 - Springer
… neurodegenerative disease caused by a CAG repeat expansion in exon 1 of the … gene (HD)
also known as IT15. Despite the disease being caused by dysfunction of a single gene, …

Single amino acid and trinucleotide repeats: function and evolution

N Faux - Tandem repeat polymorphisms: genetic plasticity …, 2012 - Springer
… : interspersed repeats or transposable elements, and tandem repeats, which include
microsatellites, minisatellites, satellites and simple sequence repeats, such as trinucleotide repeats (…