Targeting human endothelial cells with glutathione and alanine increases the crossing of a polypeptide nanocarrier through a blood–brain barrier model and entry to …
Nanoparticles (NPs) are the focus of research efforts that aim to develop successful drug
delivery systems for the brain. Polypeptide nanocarriers are versatile platforms and combine
high functionality with good biocompatibility and biodegradability. The key to the efficient
brain delivery of NPs is the specific targeting of cerebral endothelial cells that form the blood–
brain barrier (BBB). We have previously discovered that the combination of two different
ligands of BBB nutrient transporters, alanine and glutathione, increases the permeability of …
delivery systems for the brain. Polypeptide nanocarriers are versatile platforms and combine
high functionality with good biocompatibility and biodegradability. The key to the efficient
brain delivery of NPs is the specific targeting of cerebral endothelial cells that form the blood–
brain barrier (BBB). We have previously discovered that the combination of two different
ligands of BBB nutrient transporters, alanine and glutathione, increases the permeability of …
Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood–Brain Barrier Model and Entry …
Nanoparticles (NPs) are the focus of research efforts that aim to develop successful drug
delivery systems for the brain. Polypeptide nanocarriers are versatile platforms and combine
high functionality with good biocompatibility and biodegradability. The key to the efficient
brain delivery of NPs is the specific targeting of cerebral endothelial cells that form the blood–
brain barrier (BBB). We have previously discovered that the combination of two different
ligands of BBB nutrient transporters, alanine and glutathione, increases the permeability of …
delivery systems for the brain. Polypeptide nanocarriers are versatile platforms and combine
high functionality with good biocompatibility and biodegradability. The key to the efficient
brain delivery of NPs is the specific targeting of cerebral endothelial cells that form the blood–
brain barrier (BBB). We have previously discovered that the combination of two different
ligands of BBB nutrient transporters, alanine and glutathione, increases the permeability of …
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