Tat peptide and hexadecylphosphocholine introduction into pegylated liposomal doxorubicin: An in vitro and in vivo study on drug cellular delivery, release …
We have investigated the co-addition of hexadecylphosphocholine (HePC) and a Tat
derived peptide (Tat), coupled to Maleimide-PEG2000-DSPE pegylated liposomal
doxorubicin (PLD) in many respects, including drug and liposome cellular delivery, drug
release, biodistribution, in vivo cell delivery and antitumor activity. The liposomes were
HePC-free and-containing liposomes, from which liposomes with 25, 50, 100 and 200
numbers of Tat/liposome were prepared. Similarly, DiI-C18 (3)-model liposomes (DiI-L and …
derived peptide (Tat), coupled to Maleimide-PEG2000-DSPE pegylated liposomal
doxorubicin (PLD) in many respects, including drug and liposome cellular delivery, drug
release, biodistribution, in vivo cell delivery and antitumor activity. The liposomes were
HePC-free and-containing liposomes, from which liposomes with 25, 50, 100 and 200
numbers of Tat/liposome were prepared. Similarly, DiI-C18 (3)-model liposomes (DiI-L and …
[PDF][PDF] Tat peptide and Hexadecylphosphocholine introduction
MTAB Shiva - International journal of pharmaceutics, 2016 - academia.edu
We have investigated the co-addition of Hexadecylphosphocholine (HePC) and a Tat
derived peptide (Tat), coupled to Maleimide-PEG2000-DSPE Pegylated liposomal
doxorubicin (PLD) in many respects, including drug and liposome cellular delivery, drug
release, biodistribution, in vivo cell delivery and antitumor activity. The liposomes were
HePC–free and-containing liposomes, from which liposomes with 25, 50, 100 and 200
numbers of Tat/liposome were prepared. Similarly, DiI-C18 (3)-model liposomes (DiI-L and …
derived peptide (Tat), coupled to Maleimide-PEG2000-DSPE Pegylated liposomal
doxorubicin (PLD) in many respects, including drug and liposome cellular delivery, drug
release, biodistribution, in vivo cell delivery and antitumor activity. The liposomes were
HePC–free and-containing liposomes, from which liposomes with 25, 50, 100 and 200
numbers of Tat/liposome were prepared. Similarly, DiI-C18 (3)-model liposomes (DiI-L and …
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