Telomerase regulation

C Cifuentes-Rojas, DE Shippen - Mutation research/Fundamental and …, 2012 - Elsevier
… the recent advances in understanding telomerase regulation. … regulation of telomerase is
supported by the observation that TERT mRNA levels do not always correlate with telomerase

Telomerase regulation from beginning to the end

DE MacNeil, HJ Bensoussan, C Autexier - Genes, 2016 - mdpi.com
telomerase to maintain telomeres throughout rapid cellular proliferation [5]. Additionally,
defects in telomerase … As such, greater knowledge of telomerase regulation and its contribution …

Telomerase regulation and stem cell behaviour

I Flores, R Benetti, MA Blasco - Current opinion in cell biology, 2006 - Elsevier
… and to enhance the efficacy of telomerase inhibitors in human cancer cells [46]. All together,
these findings underline the importance and complexity of telomerase regulation in order to …

Human telomerase and its regulation

YS Cong, WE Wright, JW Shay - Microbiology and molecular …, 2002 - Am Soc Microbiol
… The modulation of telomerase activity may therefore have … of the telomerase complex and
attempts to provide an update on the molecular mechanisms of human telomerase regulation. …

Telomerase: regulation, function and transformation

CK Dong, K Masutomi, WC Hahn - Critical reviews in oncology/hematology, 2005 - Elsevier
… express low levels of telomerase, the ribonucleoprotein … most cancers exhibit constitutive
telomerase expression and maintain … support the concept that telomerase plays multiple roles in …

Telomerase regulation: not just flipping the switch

DL Aisner, WE Wright, JW Shay - Current opinion in genetics & …, 2002 - Elsevier
… normal controls in progression to malignancy, understanding the role of signal transduction
in telomerase regulation is also key to our understanding of telomerase regulation in cancer. …

Telomerase regulation: a role for epigenetics

F Dogan, NR Forsyth - Cancers, 2021 - mdpi.com
… in the regulation of TERT expression and telomerase activity. … mechanisms behind telomerase
regulation holds important … will focus on the role of epigenetics in telomerase regulation. …

Human telomerase activity regulation

A Wojtyla, M Gladych, B Rubis - Molecular biology reports, 2011 - Springer
… Thus, we show that the telomerase expression targeting cannot be the only possibility to …
of numerous telomerase regulation mechanisms that take place after telomerase subunits …

How telomerase reaches its end: mechanism of telomerase regulation by the telomeric complex

A Bianchi, D Shore - Molecular cell, 2008 - cell.com
… and telomerase-promoting ones bound at single-stranded terminal DNA overhangs appears
to modulate telomerase … on the mechanism of telomerase regulation at chromosome ends in …

Studies of the molecular mechanisms in the regulation of telomerase activity

JUNP LIU - The FASEB Journal, 1999 - Wiley Online Library
… in regulating telomerase gene expression, structure, and function at the molecular level.
Although the mechanisms of telomerase regulation, … of the regulation of telomerase activity will …