Tetralogy of Fallot (ToF) occurs in approximately 1 in 3600 live births and accounts for 3.5%
of infants born with congenital heart disease. Surgical repair was first introduced in the
1950s and there is now a large population of adults with repaired tetralogy. Many of the
short term aspects of management have been resolved, although whether symptomatic
neonates should undergo primary repair or first be palliated remains debatable. In 2001,
independently validated data pooled from all 13 centres performing cardiac surgery in the …

… The aim of this work is to make an overview of the Tetralogy of Fallot pathology, from fetal
life to adulthood, emphasizing the adverse outcomes, their monitoring and management. …
With surgical treatment over 85% of children survive to adulthood. [10] The patients who
survive into adulthood without surgical treatment require unique management based on
their individual anatomy and physiology. …