The β-lactamase gene regulator AmpR is a tetramer that recognizes and binds the D-Ala-D-Ala motif of its repressor UDP-N-acetylmuramic acid (MurNAc) …
Inducible expression of chromosomal AmpC β-lactamase is a major cause of β-lactam
antibiotic resistance in the Gram-negative bacteria Pseudomonas aeruginosa and
Enterobacteriaceae. AmpC expression is induced by the LysR-type transcriptional regulator
(LTTR) AmpR, which activates ampC expression in response to changes in peptidoglycan
(PG) metabolite levels that occur during exposure to β-lactams. Under normal conditions,
AmpR represses ampC transcription by binding the PG precursor UDP-N-acetylmuramic …
antibiotic resistance in the Gram-negative bacteria Pseudomonas aeruginosa and
Enterobacteriaceae. AmpC expression is induced by the LysR-type transcriptional regulator
(LTTR) AmpR, which activates ampC expression in response to changes in peptidoglycan
(PG) metabolite levels that occur during exposure to β-lactams. Under normal conditions,
AmpR represses ampC transcription by binding the PG precursor UDP-N-acetylmuramic …
以上显示的是最相近的搜索结果。 查看全部搜索结果