[HTML][HTML] The Alzheimer's Knowledge Base: A Knowledge Graph for Alzheimer Disease Research
Background As global populations age and become susceptible to neurodegenerative
illnesses, new therapies for Alzheimer disease (AD) are urgently needed. Existing data
resources for drug discovery and repurposing fail to capture relationships central to the
disease's etiology and response to drugs. Objective We designed the Alzheimer's
Knowledge Base (AlzKB) to alleviate this need by providing a comprehensive knowledge
representation of AD etiology and candidate therapeutics. Methods We designed the AlzKB …
illnesses, new therapies for Alzheimer disease (AD) are urgently needed. Existing data
resources for drug discovery and repurposing fail to capture relationships central to the
disease's etiology and response to drugs. Objective We designed the Alzheimer's
Knowledge Base (AlzKB) to alleviate this need by providing a comprehensive knowledge
representation of AD etiology and candidate therapeutics. Methods We designed the AlzKB …
[PDF][PDF] The Alzheimer's Knowledge Base: A Knowledge Graph for Alzheimer Disease Research
Background: As global populations age and become susceptible to neurodegenerative
illnesses, new therapies for Alzheimer disease (AD) are urgently needed. Existing data
resources for drug discovery and repurposing fail to capture relationships central to the
disease's etiology and response to drugs. Objective: We designed the Alzheimer's
Knowledge Base (AlzKB) to alleviate this need by providing a comprehensive knowledge
representation of AD etiology and candidate therapeutics. Methods: We designed the AlzKB …
illnesses, new therapies for Alzheimer disease (AD) are urgently needed. Existing data
resources for drug discovery and repurposing fail to capture relationships central to the
disease's etiology and response to drugs. Objective: We designed the Alzheimer's
Knowledge Base (AlzKB) to alleviate this need by providing a comprehensive knowledge
representation of AD etiology and candidate therapeutics. Methods: We designed the AlzKB …
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