The CTX-M β-lactamase pandemic

R Cantón, TM Coque - Current opinion in microbiology, 2006 - Elsevier
… (CTX-M-9 or CTX-M-14 producers) or epidemic clones associated with specific enzymes such
as CTX-M-… might have contributed to the current pandemic CTX-M β-lactamase scenario. …

The first major extended‐spectrum βlactamase outbreak in Scandinavia was caused by clonal spread of a multiresistant Klebsiella pneumoniae producing CTXM …

B Lytsy, L Sandegren, EVA Tano, E Torell… - Apmis, 2008 - Wiley Online Library
… Among the CTX-M family, CTX-M-15 belongs to the more expansive types, and is … CTX-M-9
predominates (15, 19). Some reports describe CTX-M-15 as being linked with epidemic

Emergence of human pandemic O25:H4-ST131 CTX-M-15 extended-spectrum-β-lactamase-producing Escherichia coli among companion animals

C Ewers, M Grobbel, I Stamm, PA Kopp… - Journal of …, 2010 - academic.oup.com
… harboured a CTX-M-15-type β-lactamase enzyme while one strain possessed an SHV-12-type
ESBL. Macrorestriction analysis revealed a cluster formation of six of the animal CTX-M-…

Outbreak of CTX-M-15 Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae ST394 in a French Intensive Care Unit Dedicated to COVID-19

C Emeraud, S Figueiredo, RA Bonnin, M Khecharem… - Pathogens, 2021 - mdpi.com
… In this context, the risk of emergence of a nosocomial outbreak was thought to be at its
lowest level. However, we report here a large outbreak of CTX-M-15-producing Klebsiella …

Detection of pandemic B2-O25-ST131 Escherichia coli harbouring the CTX-M-9 extended-spectrum β-lactamase type in a feral urban brown rat (Rattus norvegicus)

S Guenther, M Grobbel, J Beutlich… - Journal of …, 2010 - academic.oup.com
… electropherogram of XbaI-restricted genomic DNA of the CTX-M-9-type ESBL-producing E.
… /05; O25b-CTX-M-15-ST131) representing the human pandemic virulent group of clonally …

An outbreak of a CTX-M-type β-lactamase-producing Klebsiella pneumoniae: the importance of using cefpodoxime to detect extended-spectrum β-lactamases

NP Brenwald, G Jevons, JM Andrews… - Journal of …, 2003 - academic.oup.com
… for the outbreak. This is the first report of an outbreak involving a CTX-M β-lactamase-…
Although the MIC of ceftazidime for the CTX-M-producing isolates was increased compared with …

[HTML][HTML] Human pandemic K27-ST392 CTX-M-15 extended-spectrum β-lactamase-positive Klebsiella pneumoniae: a one health clone threatening companion …

LCBA da Silva, B Cardoso, H Fontana, F Esposito… - One Health, 2022 - Elsevier
Extended spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae is a medically
important pathogen that commonly causes human nosocomial infections. Since veterinary …

Detection of CTX-M-15 extended-spectrum β-lactamase in the United Kingdom

S Mushtaq, N Woodford, N Potz… - Journal of Antimicrobial …, 2003 - academic.oup.com
… Previously, CTX-M-9 and a CTX-M-25-like enzyme were … and CTX-M-15 each belong to
distinct and different CTX-M … An outbreak of a CTX-M-type β-lactamase-producing Klebsiella …

CTX-M: changing the face of ESBLs in the UK

DM Livermore, PM Hawkey - Journal of Antimicrobial …, 2005 - academic.oup.com
outbreak of CTX-M producers in the UK occurred in 2001 and involved Klebsiella pneumoniae
with CTX-M… Although most CTX-M β-lactamase producers submitted to the reference …

CTX-M-5, a Novel Cefotaxime-Hydrolyzing β-Lactamase from an Outbreak of Salmonella typhimuriumin Latvia

PA Bradford, Y Yang, D Sahm, I Grope… - Antimicrobial agents …, 1998 - Am Soc Microbiol
… member of the CTX-M cefotaxime-hydrolyzing β-lactamase family, designated CTX-M-5. …
β-lactamase, CTX-M-5. It is interesting that in this small family of cefotaxime-hydrolyzing …