The East Asian gut microbiome is distinct from colocalized White subjects and connected to metabolic health

QY Ang, DL Alba, V Upadhyay, JE Bisanz, J Cai… - Elife, 2021 - elifesciences.org
East Asians (EAs) experience worse metabolic health outcomes compared to other ethnic
groups at lower body mass indices; however, the potential role of the gut microbiota in
contributing to these health disparities remains unknown. We conducted a multi-omic study
of 46 lean and obese East Asian and White participants living in the San Francisco Bay
Area, revealing marked differences between ethnic groups in bacterial richness and
community structure. White individuals were enriched for the mucin-degrading Akkermansia …

[PDF][PDF] The East Asian Gut Microbiome is Distinct from Colocalized White Subjects and Connected to Metabolic Health 2

D Center - pdfs.semanticscholar.org
… We then used microbiome transplantations to assess the stability of ethnicity-associated 81
differences in the gut microbiota in the context of genetically identical mice fed the same diet.
82 … associated signatures within the gut microbiota of lean EA vs. W individuals that are 212 …
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