The development of machine learning models for electrocatalysts requires a broad set of training data to enable their use across a wide variety of materials. One class of materials that currently lacks sufficient training data is oxides, which are critical for the development of Oxygen Evolution Reaction (OER) catalysts. To address this, we developed the Open Catalyst 2022 (OC22) dataset, consisting of 62,331 Density Functional Theory (DFT) relaxations (∼9,854,504 single point calculations) across a range of oxide materials, coverages, and adsorbates. We define generalized total energy tasks that enable property prediction beyond adsorption energies; we test baseline performance of several graph neural networks; and we provide predefined dataset splits to establish clear benchmarks for future efforts. In the most general task, GemNet-OC sees a ∼36% improvement in energy predictions when combining the chemically dissimilar Open Catalyst 2020 Data set (OC20) and OC22 datasets via fine-tuning. Similarly, we achieved a ∼19% improvement in total energy predictions on OC20 and a ∼9% improvement in force predictions in OC22 when using joint training. We demonstrate the practical utility of a top performing model by capturing literature adsorption energies and important OER scaling relationships. We expect OC22 to provide an important benchmark for models seeking to incorporate intricate long-range electrostatic and magnetic interactions in oxide surfaces. Data set and baseline models are open sourced, and a public leaderboard is available to encourage continued community developments on the total energy tasks and data.