The RTS, S malaria vaccine

S Casares, TD Brumeanu, TL Richie - Vaccine, 2010 - Elsevier
… the use of different vaccine platforms for priming and … malaria vaccines in general, and
RTS,S in particular. The rationale behind this strategy is simple: if a particular vaccine platform is

The RTS, S malaria vaccine: Current impact and foundation for the future

JG Beeson, L Kurtovic, C Valim, KP Asante… - Science Translational …, 2022 - science.org
… Obtaining an effective malaria vaccine has … a malaria vaccine called RTS,S for widespread
use in young children was an important milestone. RTS,S is a virus-like particle (VLP) vaccine

The development of the RTS, S malaria vaccine candidate: challenges and lessons

WR Ballou - Parasite immunology, 2009 - Wiley Online Library
… a consultation with the malaria vaccine community and leading statisticians that helped
reassure that the methodologies that we have used in our malaria vaccine field trials and the …

Long-term efficacy and immune responses following immunization with the RTS, S malaria vaccine

JA Stoute, KE Kester, U Krzych… - The Journal of …, 1998 - academic.oup.com
… The RTS,S malaria vaccine formulations we studied were designed to induce strong
immune responses to the P. falciparum CS antigen. Our data indicate that antibody and cellular …

RTS, S malaria vaccine and increased mortality in girls

SL Klein, F Shann, WJ Moss, CS Benn, P Aaby - MBio, 2016 - Am Soc Microbiol
malaria causes approximately 10% of all deaths in children under 5 years of age. The
RTS,S/AS01 malaria vaccine … to be 18 to 36% efficacious against clinical malaria (1). Although the …

RTS, S malaria vaccine pilots in three African countries

P Adepoju - The Lancet, 2019 - thelancet.com
RTS,S malaria vaccine. Anthony Nsiah-Asare, the director-general of the Ghana Health Service,
described the malaria vaccine … the control and elimination of malaria. The official launch …

Systems analysis of protective immune responses to RTS, S malaria vaccination in humans

D Kazmin, HI Nakaya, EK Lee… - Proceedings of the …, 2017 - National Acad Sciences
… The RTS,S malaria vaccine is the most advanced malaria vaccine candidate to be tested in
RTS,S is an advanced malaria vaccine candidate and confers significant protection against …

[HTML][HTML] Modelling the cost-effectiveness of introducing the RTS, S malaria vaccine relative to scaling up other malaria interventions in sub-Saharan Africa

P Winskill, PGT Walker, JT Griffin, AC Ghani - BMJ Global Health, 2017 - gh.bmj.com
… We find that implementing the RTS,S malaria vaccine generally only enters the optimal …
seasonal malaria chemoprevention in settings where it is recommended, has been achieved. …

Multifunctional antibodies are induced by the RTS, S malaria vaccine and associated with protection in a phase 1/2a trial

L Kurtovic, T Atre, G Feng, BD Wines… - The Journal of …, 2021 - academic.oup.com
RTS,S is the leading malaria vaccine candidate but only confers partial efficacy against malaria
… may be a strategy to improve the protective efficacy of RTS,S or other malaria vaccines. …

Implementation strategies for the introduction of the RTS, S/AS01 (RTS, S) malaria vaccine in countries with areas of highly seasonal transmission: workshop meeting …

CS Merle - Malaria journal, 2023 - Springer
… Programmes on Immunization (EPI) and National Malaria Control … RTS,S is the first malaria
vaccine to be recommended by the … pilot implementation of the vaccine in Ghana, Kenya and …