The allenic Alder-ene reaction: constitutional group selectivity and its application to the synthesis of ovalicin
KM Brummond, JM McCabe - Tetrahedron, 2006 - Elsevier
The scope of the novel allenic Alder-ene reaction using Rh (I) and Ir (I) catalysts has been
extended to differentially substituted 1, 1, 3-trisubstituted allenes. This allenyl substitution
pattern can give three possible cross-conjugated triene products. The selectivity of this
transformation can be controlled by varying reaction temperature, solvent, and catalyst.
Progress toward the synthesis of ovalicin using this triene forming protocol is described.
extended to differentially substituted 1, 1, 3-trisubstituted allenes. This allenyl substitution
pattern can give three possible cross-conjugated triene products. The selectivity of this
transformation can be controlled by varying reaction temperature, solvent, and catalyst.
Progress toward the synthesis of ovalicin using this triene forming protocol is described.
以上显示的是最相近的搜索结果。 查看全部搜索结果