important in the prevention of CVD. The PREDIMED trial tested a relatively low-fat diet
versus a high-fat Mediterranean diet (MedDiet) for the primary prevention of CVD. The
resulting reduction of the CV composite outcome resulted in a paradigm shift in CV nutrition.
Though many dietary factors likely contributed to this effect, this review focuses on the
influence of the MedDiet on endogenous antioxidant systems and the effect of dietary …