… in α-sarcin [13]. Accordingly, this cytotoxin might behave as a cyclizing ribonuclease, although
… In this work, we present evidence revealing that α-sarcin would catalyze the hydrolysis of …

… in K-sarcin [13]. Accordingly, this cytotoxin might behave as a cyclizing ribonuclease, although
… In this work, we present evidence revealing that K-sarcin would catalyze the hydrolysis of …

… Many steps of the cytotoxic process have been elucidated at … of α-sarcin and restrictocin with
those of RNase T1 and RNase U2 … of all these enzymes as cyclizing RNases. Analysis of the …

… This study is focused on α-sarcin, a cytotoxin produced by the … α-Sarcin is the most
representative member of a distinctive … shown that α-sarcin behaves as a cyclizing ribonuclease …

… They are cyclizing RNases displaying the general acid-base … in α-sarcin produces a non-toxic
but active ribonuclease with … -cytotoxic and hypoallergenic mutant variants of Aspf1 and α-…

… The cytotoxin a-sarcin behaves as a cyclizing ribonuclease. … structure of the cytotoxic
ribonuclease a-sarcin reveals the structural … The primary structure of the cytotoxin a-sarcin. J. Biol. …

… Ribotoxins and non-cytotoxic ribonucleases of the RNase T1 … residues of α-sarcin (His 50,
Glu 96, and His 137) and RNase T1 … It is well known that ribotoxins are cyclizing ribonucleases …

… cyclizing [3] ribonuclease has been revealed to be cytotoxic … , The cytotoxin r-sarcin behaves
as a cyclizing ribonuclease. … 1993, Kinetic study of the cytotoxic effect of 2sarcin, a ribosome-…

… had a cytotoxic effect … α-Sarcin, a low molecular weight ribonuclease produced by Aspergillus
giganteus, belongs to the type I group of ribosome inactivating proteins [112, 113]. α-Sarcin …

… Fungal ribotoxins are toxic secreted ribonucleases that … [18], [19] showing that it is a cyclizing
RNase [14]. Cleavage of its … (α-sarcin H137Q) devoid of ribonucleolytic and cytotoxic activity …