… To demonstrate the presence of useful signals in the disease regulome, we analyzed a … ,
graft versus host disease, asthma, allergies, a number of autoimmune and infectious diseases. …

… (TCGA) and used the differential regulome methodology that … to identify the regulatory
patterns that are different for each … differential regulome networks between healthy and disease …

… structures assembled via hydrogen bonds interconnecting the 8 different loops and helices
defining the classical ‘clover-like’ secondary structure (Fig. 1a–c). These include from 5’ to 3’ …

… In this study, we evaluate drug−disease correlations at the regulome level for predicting …
To identify the commonality of different diseases, we applied Uniform Manifold Approximation …

… The regulome of a miRNA essentially consists of modules such … The regulome also considers
associated diseases when a … different diseases, in which the effect of a certain disease on …

… To ask how activity-regulated gene expression varies across the different cell types within
our cultures, we performed scRNAseq on hGN cultures after exposure to elevated levels of …

… The aim of this review is to summarize the results of the study of the miRNA regulome, …
in cells and organs that are the target of the disease in humans, ie atherosclerotic plaques, in …

… regions, we measured the level of H3K27Ac at the different clusters in chromatin from WT, …
the IRF8/IRF1 regulome and genetic loci contributing to susceptibility to inflammatory diseases …

… We binned the interaction matrix at different resolutions and corrected it with iterative
correction for downstream analysis 58 . All Hi-C QC metrics are summarized in Supplementary …

… reference for comparing disease-associated regulomes. … variation in the T-cell regulome,
because it emerged as the most … Top: differential TF occupancy, defined as the TF occupancy …