reduction of dietary nitrate (NO 3) to nitrite (NO 2) to NO. The combined effect of vitamin C
and NO 3 supplementation is relatively unexplored in untreated hypercholesterolemia. Aims
We aimed to examine whether co-administration of vitamin C and nitrate for 4-weeks would
improve endothelial function (primary outcome), plasma NO metabolites, oxidative stress,
and blood lipids (secondary outcomes). Methods Subjects 50–70 years of age with low …