The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data
… Antimalarial Resistance Network (WWARN) AS-AQ … - BMC medicine, 2015 - Springer
Abstract Background Artesunate-amodiaquine (AS-AQ) is one of the most widely used
artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium
falciparum malaria in Africa. We investigated the impact of different dosing strategies on the
efficacy of this combination for the treatment of falciparum malaria. Methods Individual
patient data from AS-AQ clinical trials were pooled using the WorldWide Antimalarial
Resistance Network (WWARN) standardised methodology. Risk factors for treatment failure …
artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium
falciparum malaria in Africa. We investigated the impact of different dosing strategies on the
efficacy of this combination for the treatment of falciparum malaria. Methods Individual
patient data from AS-AQ clinical trials were pooled using the WorldWide Antimalarial
Resistance Network (WWARN) standardised methodology. Risk factors for treatment failure …
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.
WWARNW AS-AQ, MA Adjuik, R Allan… - BMC …, 2015 - researchonline.lshtm.ac.uk
BACKGROUND: Artesunate-amodiaquine (AS-AQ) is one of the most widely used
artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium
falciparum malaria in Africa. We investigated the impact of different dosing strategies on the
efficacy of this combination for the treatment of falciparum malaria. METHODS: Individual
patient data from AS-AQ clinical trials were pooled using the WorldWide Antimalarial
Resistance Network (WWARN) standardised methodology. Risk factors for treatment failure …
artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium
falciparum malaria in Africa. We investigated the impact of different dosing strategies on the
efficacy of this combination for the treatment of falciparum malaria. METHODS: Individual
patient data from AS-AQ clinical trials were pooled using the WorldWide Antimalarial
Resistance Network (WWARN) standardised methodology. Risk factors for treatment failure …
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