[PDF][PDF] The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

JR Elliott Middleton, C Kandaswami… - Pharmacol Rev, 2000 - academia.edu
… of this group of compounds may significantly affect the function of various mammalian cellular
systems. Anti-inflammatory flavonoids were discussed by Lewis (1989), and their potential …

The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

E Middleton, C Kandaswami, TC Theoharides - Pharmacological reviews, 2000 - ASPET
Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible
for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil, tea…

The effects of flavonoids in cardiovascular diseases

L Ciumărnean, MV Milaciu, O Runcan, ȘC Vesa… - Molecules, 2020 - mdpi.com
… Quercetin also decreases oxidative stress in the heart and … citrus flavonoids inhibit the synthesis
of various pro-inflammatory … Apigenin has a potent anti-inflammatory effect, which may in …

Antiartherosclerotic effects of plant flavonoids

S Salvamani, B Gunasekaran… - BioMed research …, 2014 - Wiley Online Library
… diseases such as strokes, heart attacks, and peripheral … to various side effects, the plants
flavonoids with antiartherosclerotic … anti-inflammatory, anticancer, and positive effects on sex …

Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease

A García-Lafuente, E Guillamón, A Villares… - Inflammation …, 2009 - Springer
… Exposure of mammalian cells to LPS has been shown to activate MAPK signaling cascades
[108]. Xagorari et al. [109] have shown that the exposure of RAW 264.7 macrophages to …

Flavonoids and cardiovascular disease

M Gross - Pharmaceutical biology, 2004 - Taylor & Francis
… Also, the influence of human flavonoid metabolism on anti-inflammatory … of flavonoids in
the prevention of coronary heart disease. Thus, the influence of flavonoids on inflammation in …

Anti-inflammatory effects of flavonoids

SJ Maleki, JF Crespo, B Cabanillas - Food chemistry, 2019 - Elsevier
… the impact that flavonoids, the most abundant polyphenols in the diet, have on inflammatory
… be protective against cardiac hypertrophy induced by pressure overload. Baicalin improved …

Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity

O Benavente-Garcia, J Castillo - Journal of agricultural and food …, 2008 - ACS Publications
… In coronary heart disease, the protective effects of flavonoids … that flavonoids decrease
the risk of coronary heart disease … Progression from the G1 to S phase in mammalian cells is …

Anti-inflammatory plant flavonoids and cellular action mechanisms

HP Kim, KH Son, HW Chang, SS Kang - Journal of pharmacological …, 2004 - jstage.jst.go.jp
… of varieties of flavonoids need to be further elucidated. This review summarizes the effect
of flavonoids on eicosanoid and nitric oxide generating enzymes and the effect on expression …

Biological properties of flavonoids pertaining to inflammation

JA Manthey - Microcirculation, 2000 - Taylor & Francis
… with flavonoids may also be beneficial. The purpose of this review is to summarize how plant
flavonoids attenuate inflammation … by silibinin in human cells. Life Sci 58:1591–1600. 12. …