The pilocarpine animal model of status epilepticus is a well-established, clinically
translatable model that satisfies all of the criteria essential for an animal model of status
epilepticus: a latency period followed by spontaneous recurrent seizures, replication of
behavioural, electrographic, metabolic, and neuropathological changes, as well as,
pharmacoresistance to anti-epileptic drugs similar to that observed in human status
epilepticus. However, this model is also characterized by high mortality rates and studies in …