Materials and Methods: In this cross-sectional study, of 246 clinical specimen were collected from educational hospitals of Hamadan university of medical sciences, 12 isolates of S. maltophilia were collected in 2015. After the culture, isolates were verified by standard biochemical methods. Antibiotic susceptibility was determined against 13 antibiotics. Presence of Class I and II integrons genes were tested using specific primers by PCR.
Results: In the pattern of antibiotic resistance, the highest resistance rate showed to Cefditoren, Ceftriaxone, Cefotaxime antibiotics and the lowest resistance to Amikacin, Imipenem, Ofloxacin, Trimethoprim-Sulphamethoxazole and Ciprofloxacin antibiotics were reported. All S. maltophilia strains carried class I integrons. No isolate carry class II integrons and gene cassettes.
Conclusions: The result of this study indicates a high prevalence of class I integrons in S. maltophilia isolates. Thus, identification of these resistance genes for infection control programs and to prevent the spread of resistant strains is very important.