… hadal zone remains poorly understood. Here, we sequenced and assembled the genome of
hadal sea cucumber … explored its potential mechanisms for deep-sea adaptation. First, the …

… well adapted to diverse deep-sea ecosystems, especially chemosynthetic environments. …
the genetic basis of adaptation to deep-sea extreme environments is particularly interesting. …

… and Holothuroidea (sea urchin and sea cucumber, subphylum … shallow-water and deep-sea
environments 6 . Phylogenetic … , with habitats ranging from shallow intertidal areas to hadal …

… adaptation of hadal organisms to the deep-sea environment and valuable genomic resources
that will help further clarify hadal … deep-sea species may share similar adaptive strategies. …

… are found in both deep sea and shallow water environments. Their genetic … revealed
significant disparities in the codon usage proportions among deep-sea and shallow sea cucumbers…

… deep-sea species within phyla (hadal sea cucumber and … as a result of adaptation to the HHP
and cold environment. … likely contribute to the adaptive strategies seen in different lineages. …

… flourish in the hostile deep-sea environment. However, few … This was a potential adaptive
strategy of gut-associated … acid pathways were missed in this kind of sea cucumber [64]. …

… , from the intertidal zone to the deep sea [105, 122], and … Finally, we describe all the publicly
available genomic and … , auricularia larvae grow in size and sense the external environment …

… and utilization indicates an adaptation strategy to meet the … Previous study of hadal sea
cucumber Paelopatides sp. Yap … immune and stress responses in sea cucumber A. japonicus 17 …

… the least challenges for genome sequencing and assembly in … genomic information from a
total of 19 sea cucumber genomes, both newly sequenced and previously reported, revealing …