The hen's egg test on chorioallantoic membrane: An alternative assay for the assessment of the irritating effect of vaccine adjuvants
A Batista-Duharte, G Jorge Murillo… - International …, 2016 - journals.sagepub.com
Local reactions are the most frequent adverse event associated with vaccines. Adjuvants are
major constituents of many vaccines and they are frequently involved in these reactions,
associated with their irritating effect and the stimulation of local inflammation. The hen's egg
test on chorioallantoic membrane (HET-CAM) is an alternative toxicological method widely
used to determine ocular irritation potential, but very few studies have demonstrated the
utility of this method for assessing the irritant properties of vaccine adjuvants. In this work …
major constituents of many vaccines and they are frequently involved in these reactions,
associated with their irritating effect and the stimulation of local inflammation. The hen's egg
test on chorioallantoic membrane (HET-CAM) is an alternative toxicological method widely
used to determine ocular irritation potential, but very few studies have demonstrated the
utility of this method for assessing the irritant properties of vaccine adjuvants. In this work …
The Hen's Egg Test on Chorioallantoic Membrane
UM Pérez, E Tur, DF Portuondo, O Pérez… - International Journal of …, 2016 - cir.nii.ac.jp
< jats: p> Local reactions are the most frequent adverse event associated with vaccines.
Adjuvants are major constituents of many vaccines and they are frequently involved in these
reactions, associated with their irritating effect and the stimulation of local inflammation. The
hen's egg test on chorioallantoic membrane (HET-CAM) is an alternative toxicological
method widely used to determine ocular irritation potential, but very few studies have
demonstrated the utility of this method for assessing the irritant properties of vaccine …
Adjuvants are major constituents of many vaccines and they are frequently involved in these
reactions, associated with their irritating effect and the stimulation of local inflammation. The
hen's egg test on chorioallantoic membrane (HET-CAM) is an alternative toxicological
method widely used to determine ocular irritation potential, but very few studies have
demonstrated the utility of this method for assessing the irritant properties of vaccine …
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