We report on the lowest-frequency detection to date of three bursts from the fast radio burst FRB 180916. J0158+ 65, observed at 328 MHz with the Sardinia Radio Telescope (SRT). The SRT observed the periodic repeater FRB 180916. J0158+ 65 for five days from 2020 February 20 to 24 during a time interval of active radio bursting, and detected the three bursts during the first hour of observations; no more bursts were detected during the remaining∼ 30 hr. Simultaneous SRT observations at 1548 MHz did not detect any bursts. Burst fluences are in the range 37 to 13 Jy ms. No relevant scattering is observed for these bursts. We also present the results of the multi-wavelength campaign we performed on FRB 180916. J0158+ 65, during the five days of the active window. Simultaneously with the SRT observations, others with different time spans were performed with the Northern Cross at 408 MHz, with XMM-Newton, NICER, INTEGRAL, AGILE, and with the TNG and two optical telescopes in Asiago, which are equipped with fast photometers. XMM-Newton obtained data simultaneously with the three bursts detected by the SRT, and determined a luminosity upper limit in the 0.3–10 keV energy range of∼ 10 45 erg s− 1 for the burst emission. AGILE obtained data simultaneously with the first burst and determined a fluence upper limit in the MeV range for millisecond timescales of