This investigation aims to examine the moderating and mediating role of public service motivation (PSM) on the relationship between organizations’ social responsibility (SR) and employee organization engagement (OE). Using a sample of employees working in four public hospitals in Egypt, the study’s hypotheses were tested using structural equation modeling. Results reported in the study indicated the following: a) PSM had a positive influence on employees’ OE; b) PSM mediated the relationship between organizations’ SR and employees’ OE; c) PSM did not moderate the relationship between organizations’ SR and employees’ OE. Overall, the model results into a partial mediation model of PSM. This investigation could be regarded as one of the first studies undertaking analyses of the relationships between organizations’ SR, PSM, and employee engagement. However, further work is still needed to provide a better understanding of the organizational factors that can help instill, nurture, or suppress PSM and employees’ OE in the public sector.