In order to examine perceptual, motivational, and hormonal mechanisms underlying differences in female sociosexuality, 72 women completed questionnaires and male facerating tasks at two different phases of their menstrual cycle. The more unrestricted women rated the male faces as healthier than the more restricted women. In addition, two methods of assessing sociosexuality (the Sociosexual Orientation Index scale and male facial ratings of one-night stand interest) indicated that restricted and unrestricted women exhibit different patterns of sociosexuality across the menstrual cycle. Both groups of women showed evidence of a periovulatory sociosexuality tactic shift (PSTS) in the direction away from their primary strategy. That is, restricted women indicated an increase in one-night stand interest during the periovulatory phase, while unrestricted women showed a trend toward a decrease in one-night stand interest during this high fertile phase. These preliminary findings suggest that activational-hormonal and cognitive-perceptual mechanisms may partly account for individual differences in female sociosexuality and mate evaluation processes within the restricted and unrestricted strategies. The results are discussed in terms of several evolutionary mating strategy theories.