The Quest for the 1p36 Tumor Suppressor

A Bagchi, AA Mills - Cancer research, 2008 - AACR
… Although several genes have been proposed as 1p36 candidate tumor suppressors, …
documenting 1p36 deletions. Hence, the search for the 1p36 tumor suppressor has continued. …

1p36 tumor suppression—a matter of dosage?

KO Henrich, M Schwab, F Westermann - Cancer research, 2012 - AACR
… Gray box, model illustrating potential interactions between 1p36 tumor suppressor … Gray
box, model illustrating potential interactions between 1p36 tumor suppressor candidates. …

Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers

S Nomoto, N Haruki, Y Tatematsu… - … and Cancer, 2000 - Wiley Online Library
… In our previous search for mutations in the TP73 gene at 1p36, we could not identify somatic
mutations in lung cancers, but did observe frequent allelic imbalance at the TP73 locus, a …

Chromosome band 1p36 contains a putative tumor suppressor gene important in the evolution of chronic myelocytic leukemia

N Mori, R Morosetti, S Spira, S Lee… - Blood, The Journal …, 1998 - ashpublications.org
… to D1S508 and distal to D1S507 (1p36). Our results suggest that a tumor suppressor
gene that frequently plays an important role in the evolution to BC resides on 1p36 in CML. …

[HTML][HTML] Adherens junctional associated protein-1: a novel 1p36 tumor suppressor candidate in gliomas

L Zeng, BE Fee, MV Rivas, J Lin… - … journal of oncology, 2014 - spandidos-publications.com
tumor suppressor-related gene may reside in this region (4,12). Although the quest for the
1p36 tumor suppressor … have tumor suppressor-like capabilities in specific tumor contexts (13–…

CHD5 is a tumor suppressor at human 1p36

A Bagchi, C Papazoglu, Y Wu, D Capurso, M Brodt… - Cell, 2007 - cell.com
… To functionally identify novel tumor suppressor genes mapping to human 1p36, we generated
mouse strains with deletions (also called deficiencies, df) or duplications (dp) of this region…

A tumor suppressor locus in familial and sporadic chordoma maps to 1p36

M Miozzo, L Dalprà, P Riva, M Volontà… - … journal of cancer, 2000 - Wiley Online Library
1p36.11, we mapped the cancer susceptibility locus in this family to the … (1p36.31) to
D1S2728 (1p36.13). Our overall findings converge on mapping to 1p36 a tumorsuppressor gene …

CHD5 , a Tumor Suppressor Gene Deleted From 1p36.31 in Neuroblastomas

T Fujita, J Igarashi, ER Okawa, T Gotoh… - … the National Cancer …, 2008 - academic.oup.com
… We also compared the expression of 12 genes from the 1p36 … fide tumor suppressor gene
and the likely target of the 1p36.… CHD5 is the tumor suppressor gene deleted from the 1p36.31 …

Expression and sequence analysis of candidates for the 1p36. 31 tumor suppressor gene deleted in neuroblastomas

ER Okawa, T Gotoh, J Manne, J Igarashi, T Fujita… - Oncogene, 2008 - nature.com
… Here, we report two additional neuroblastomas with informative 1p36.31 deletions that further
… within 1p36 or at other tumor suppressor loci in neuroblastoma. Cancer Res 61: 679–686. …

CAMTA1, a 1p36 Tumor Suppressor Candidate, Inhibits Growth and Activates Differentiation Programs in Neuroblastoma Cells

KO Henrich, T Bauer, J Schulte, V Ehemann… - Cancer research, 2011 - AACR
… Our data imply that CAMTA1 is a 1p36 tumor suppressor candidate that inhibits features of
… Together, our data suggest that CAMTA1 is a 1p36 tumor suppressor candidate that inhibits …