The relationship of lymphocyte recovery and prognosis of esophageal cancer patients with severe radiation-induced lymphopenia after chemoradiation therapy

W Deng, C Xu, A Liu, PSN van Rossum, W Deng… - Radiotherapy and …, 2019 - Elsevier
Introduction Radiation-induced lymphopenia (RIL) during therapy is associated with poor
prognosis but is often temporary and resolves after treatment completion in esophageal
cancer. How lymphocyte recovery contributes to prognosis is unknown. Methods We
reviewed 755 patients with stage I-III esophageal carcinoma who received concurrent
chemoradiation therapy (CRT) with or without surgery in 2004–2015. Complete blood
counts were obtained before, during, and at first follow-up after CRT. Lymphopenia was …
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