The role of anticoagulation in COVID-19-induced hypercoagulability

JS Rico-Mesa, D Rosas, A Ahmadian-Tehrani… - Current cardiology …, 2020 - Springer
JS Rico-Mesa, D Rosas, A Ahmadian-Tehrani, A White, AS Anderson, R Chilton
Current cardiology reports, 2020Springer
Abstract Purpose of Review We aim to provide a comprehensive analysis of
hypercoagulability in individuals affected by COVID-19. Our goal is to describe the
hypercoagulable state related to the infection and provide guidance regarding the possible
benefits of anti-coagulation with the support of evidence from current literature. Recent
Findings The incidence of thrombotic disease in individuals affected by COVID-19 is
reported as high as 31%. A significant mortality benefit has been observed with the use of …
Purpose of Review
We aim to provide a comprehensive analysis of hypercoagulability in individuals affected by COVID-19. Our goal is to describe the hypercoagulable state related to the infection and provide guidance regarding the possible benefits of anti-coagulation with the support of evidence from current literature.
Recent Findings
The incidence of thrombotic disease in individuals affected by COVID-19 is reported as high as 31%. A significant mortality benefit has been observed with the use of therapeutic anticoagulation in high-risk individuals. Literature supports the use of scoring systems, such as the sepsis-induced coagulopathy score, to risk-stratify individuals who might benefit from anticoagulation.
Summary
COVID-19-induced hypercoagulability has been demonstrated to play a significant role in overall COVID-19 outcomes. Current literature shows promising evidence with the use of therapeutic anticoagulation in high-risk individuals. Further studies are needed to better analyze the risks and benefits of anticoagulation in this specific patient population.
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